How many MPG does a 2025 Mercedes-Benz GLS580 4matic get?

The 2025 Mercedes-Benz GLS580 4matic gets 16 MPG combined according to the EPA — about 14 MPG in the city and 19 MPG on the highway. Combined MPG is a 55% city / 45% highway blend.

What is the annual fuel cost for a 2025 Mercedes-Benz GLS580 4matic?

Driving 15,000 miles a year at 16 MPG combined, the 2025 Mercedes-Benz GLS580 4matic uses about 938 gallons of fuel per year — roughly $3,283 at $3.50/gallon. Your real cost varies with local gas prices and driving style.

What is the difference between city and highway MPG on the 2025 Mercedes-Benz GLS580 4matic?

The 2025 Mercedes-Benz GLS580 4matic returns 14 MPG city and 19 MPG highway. Highway is higher because steady-speed cruising avoids the stop-and-go acceleration that burns fuel in city driving. The 16 MPG combined figure blends the two.

Is 16 MPG good for a standard sport utility vehicle 4wd?

For a standard sport utility vehicle 4wd, 16 MPG combined is on the thirstier side. Hybrid trims and smaller engines, where offered, return better numbers.

2025 Mercedes-Benz GLS580 4matic MPG

Official EPA fuel-economy rating for the 2025 Mercedes-Benz GLS580 4matic.

EPA combined fuel economy

16MPG

combined (55% city / 45% hwy)

City

MPG

Highway

MPG

Engine

Cylinders

Drive

AllWD

Class

Standard Sport Utility Vehicle 4WD

Running cost

Estimated annual fuel cost

Per year

$3,283

15,000 mi/yr

Fuel used

938 gal

per year

At gas price

$3.50

per gallon

Based on 16 MPG combined and 15,000 miles per year. Adjust for your local gas price and annual mileage.

Other Mercedes-Benz GLS580 4matic years

2026 2024 2023 2022 2021 All years →

FAQ

2025 Mercedes-Benz GLS580 4matic

How many MPG does a 2025 Mercedes-Benz GLS580 4matic get?: The 2025 Mercedes-Benz GLS580 4matic gets 16 MPG combined according to the EPA — about 14 MPG in the city and 19 MPG on the highway. Combined MPG is a 55% city / 45% highway blend.
What is the annual fuel cost for a 2025 Mercedes-Benz GLS580 4matic?: Driving 15,000 miles a year at 16 MPG combined, the 2025 Mercedes-Benz GLS580 4matic uses about 938 gallons of fuel per year — roughly $3,283 at $3.50/gallon. Your real cost varies with local gas prices and driving style.
What is the difference between city and highway MPG on the 2025 Mercedes-Benz GLS580 4matic?: The 2025 Mercedes-Benz GLS580 4matic returns 14 MPG city and 19 MPG highway. Highway is higher because steady-speed cruising avoids the stop-and-go acceleration that burns fuel in city driving. The 16 MPG combined figure blends the two.
Is 16 MPG good for a standard sport utility vehicle 4wd?: For a standard sport utility vehicle 4wd, 16 MPG combined is on the thirstier side. Hybrid trims and smaller engines, where offered, return better numbers.